Downloads Click here to download (PDF, 75 KB) It is important for fish farming that protein and amino acid requirements are known and matched for each of the fish species reared to maximise growth and health of the fish. Fish nutrition has advanced in recent years due to the development of new, balanced commercial diets…
Downloads Characterization of Microplastics using Morphologically-Directed Raman Spectroscopy by Malvern Panalytical (PDF, 2 MB) Microplastics are a global environmental and potential health issue. They can be released directly from the production or use of consumer products or the fragmentation of larger plastic objects. Geographically microplastics are present everywhere on Earth and have pervaded our food…
During an SPR experiment, there are many experimental parameters that must be controlled in order to optimize the performance of the system and to generate high-quality binding data. Of these parameters, minimizing non-specific binding (NSB) is one of the most imperative as it can directly affect the accuracy of your kinetic data. SPR experiments typically…
SPR is a label-free technique that enables you to get in depth information on how two biomolecules are interacting. This is done on a sensor inside of an instrument such as the OpenSPR or Alto. SPR instruments are primarily used to measure binding affinity and kinetics, and are becoming increasingly more affordable and accessible as…
Read on to learn about the two most common approaches for measuring binding kinetics, multi-cycle kinetics (MCK) and single-cycle kinetics (SCK), and how to select the right one for your interaction.
The term “pH” is derived from either “pondus hydrogenii” or “potentia hydrogenii”. Both are originally Latin phrases, with “pondus hydrogenii” meaning “weight of hydrogen” and “potentia hydrogenii” meaning “power of hydrogen”. The pH value is a non-dimensional number that measures how acidic or alkaline an aqueous solution is. It is defined as the negative decimal…
Downloads Ultra-fast semiconductor device and thin-film characterization in 3D at the nanoscale (PDF, 212 KB) Atomic Force Microscope (AFM) can be used to look at a variety of microfabricated devices ranging from microfluidics and photonics crystals to semiconductor devices. With the nGauge AFM, it is possible to easily obtain a three-dimensional image of the sample…
Downloads Polymers and composite research using Atomic Force Microscope (PDF, 500 KB) The nGauge Atomic Force Microscope (AFM) is a power tool for characterization of polymers and composites. In three clicks, the nGauge is able to provide both topographical and mechanical data with high spatial accuracy. Topography data is straightforward—this data is gathered by scanning…
Understanding the signaling pathways that the biomarkers can activate can help in the development of check-point immunotherapies. Surface Plasmon Resonance (SPR), is a common technique used to identify and elucidate biomarker interactions, signaling pathways, mechanism of interaction, drug discovery and development of therapeutics by providing a label-free, real-time method of determining binding kinetics and binding…
Downloads Detection of Pressure-Induced Aggregation Using Microfluidic Modulation Spectroscopy (MMS) (PDF, 1 MB) Pressure-Induced Protein Aggregation Detection: Protein aggregation is a recognized signal of instability and can lead to the loss of protein function. It is therefore crucial to detect protein aggregation early in the drug development process to inform further drug development decisions. Pressure,…